You asked for opinions? This should start the discussion and get alternative points of view going!
Rule of thumb: The higher the static compression, the lower ultimate safe boost.
Unless you are using some kind of sophisticated fuel, spark management (computer control)...an effective static compression of 8:1 to approximately 9.5:1 is probably the best compromise for a reliable, street-level boosted engine. 10:1 is a little on the high side, if you restrict boost below approximately 6-8 lbs, it probably will be O.K. The problem with boosted engines is greed, when you see what 6-8 lbs does to your power; you WILL turn up the boost! The stock, thin-wall, 5.0 liter block will crack under a blower, around 500 hp or higher, the question is only how long before it happens. You can go a little higher with an intercooler or aluminum heads or water/alcohol, NOS injection (it cools the mixture, making it denser, more stable). If the compression is much lower, the engine will be a "dog" when off boost. Much higher and you start running into spontaneous detonation. "There is a reason that diesel engines don't need spark plugs... high static compression creates enough heat to ignite the fuel without an induced spark".
Note: Your mileage will vary. If you have access to racing gas, high octane, you can raise the boost even more. If you can get an A-4/R-4 block...you can safely go above 800 hp. The new Dart, sportsman blocks are a lesser alternative. Some people swear by the thicker ribs of the "Mexican" blocks. However, some authorities explain that the "Mexican" block is thicker, only because the foundry produced inconsistent metal, too much porosity, so the engineers decided to compensate by making the blocks thicker. If everything is up to spec, you get a really good block. If not, it is no better than any other stock block.