Listen to Ross (my427stang). He offered some great advice and has lots of FE experience.
I specialize in Ford engines and do more than a fair share of FE's... Here's some info that may help you out.
1. Scat over Eagle. No execptions. Every time I have read of an aftermarket FE crankshaft breaking, it's been an Eagle. They tend to break right behind the 1/5 rod journal.
2. Go with as much stroke as you can. All of the Scat FE cranks are generally the same price. No reason at all to pass up cubic inches and horsepower.
3. If you're wanting an "off-the-shelf" deal, I would have no qualms about going 4.080" with a 352 block. Ross did point out that a sonic test would be prudent. I agree. I also don't know anyone that charges $250 to do one....????? The .030" 390 stroker kit combos would have a rotating assembly in your hands pretty quickly. If you're wanting to save the cylinders and just bore/hone enough to make the cylinders straight and round, then a custom piston would be a good option. No issues with heating with larger bore sizes. That seems to be one of those internet wives' tales that get passed around with nothing to support them.
I like to use more modern ring pack dimensions (something like a 1.5/1.5/3mm) and sometimes a custom piston will give you better design options.
4. I have a few camshafts that I like to use with my 445 engines and I would be happy to give you a recommendation based on what your budget is and what your goals are.
5. As for cylinder heads, it's really hard to beat an aftermarket aluminum head in performance and value. You can weigh the price of a good Edelbrock/BBM/Survival Motorsports head against the cost of taking a set of factory pieces, pressure testing them, surfacing them, guide work, valve job, cutting them for modern seals, adding valves, etc. You will most likely find that you can get a 270 cfm head for about the price of reworking a set of factory 220 cfm pieces.
You mentioned speaking to Barry on the first page. He will certainly not steer you in the wrong direction and will be a wealth of information for you. I'd be more than happy to help you as well if you need some direction. You can hop on my website and take a look at some of the combos on my dyno results page. Lykins Motorsports, LLC
There are a few guys out there in FE land who are very knowledgeable and have tons of FE experience. There is at least one poster on this thread who just seems to be a good Google searcher...